Article
Interferon gamma and Interleukin 10 polymorphisms in Brazilian patients with systemic lupus erythematosus.
Molecular biology reports - 1 Jan 2014
da Silva Hildson Dornelas Angelo, da Silva Alex Paulino, da Silva Helker Albuquerque, Asano Nadja Maria Jorge, Maia Maria de Mascena Diniz, de Souza Paulo Roberto Eleutério
Abstract excerpt
The pathogenesis of systemic lupus erythematosus (SLE) is complex, with several susceptibility genes and environmental factors involved in its development and clinical manifestation. Currently, there is a great amount of interest in the identification of biomarkers, as cytokines, that can quantify the susceptibility of SLE, the risk of future organ involvement, and association of their changes with disease...
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