Article
C-reactive protein gene polymorphisms in disease susceptibility and clinical manifestations of Korean systemic lupus erythematosus.
The Journal of rheumatology - 1 Oct 2009
Kim Hyoun-Ah, Chun Hye-Young, Kim Seung-Hyun, Park Hae-Sim, Suh Chang-Hee
Abstract excerpt
OBJECTIVE: C-reactive protein (CRP) is a sensitive marker of inflammation. It is hypothesized that polymorphism of CRP gene contributes to susceptibility to systemic lupus erythematosus (SLE). We tested this hypothesis by identifying CRP gene polymorphisms in Korean patients with SLE. METHODS: Approximately 1.5 kb of CRP promoter region was screened for single nucleotide polymorphism (SNP) using direct sequencing...
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