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Article

Interleukin-6 promoter polymorphisms -174 G/C in Brazilian patients with systemic lupus erythematosus.

Human immunology - 1 Sept 2013

Asano Nadja Maria, Angelo Hildson Dornelas, da Silva Helker Albuquerque, Maia Maria Mascena, Lins Otavio Gomes, Souza Paulo Eleutério

Abstract excerpt

To investigate the association of the IL-6 gene promoter polymorphism (-174 G/C) with SLE susceptibility and disease features in Brazilian patients, a case-control study of 80 lupus cases and 60 volunteer healthy women was performed. Genotyping was carried out by polymerase chain reaction and PCR product was digested by HSP92II restriction enzyme, being after visualized in polyacrylamide gel. There were...

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PMID: 23770252
DOI: 10.1016/j.humimm.2013.05.015

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