Article
Association study of CRP gene in systemic sclerosis in European Caucasian population.
Rheumatology international - 1 Mar 2014
Wipff Julien, Dieudé Philippe, Avouac Jérôme, Hachulla Eric, Cracowski Jean-Luc, Diot Elisabeth, Mouthon Luc, Sibilia Jean, Tiev Kiet, Meyer Olivier, Kahan André, Boileau Catherine, Allanore Yannick
Abstract excerpt
Opsonization and apoptotic cell elements are critical in systemic lupus erythematosus (SLE) and could act through the activation of the innate immunity. C-reactive protein (CRP) belongs to opsonins, and polymorphisms of CRP gene have been shown to be associated with SLE susceptibility. Accumulati...
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