Article
Association of interleukin-10 promoter haplotypes with disease susceptibility and IL-10 levels in Mexican patients with systemic lupus erythematosus.
Clinical and experimental medicine - 1 Nov 2015
Palafox-Sánchez Claudia Azucena, Oregon-Romero Edith, Salazar-Camarena Diana Celeste, Valle Yeminia Maribel, Machado-Contreras Jesús René, Cruz Alvaro, Orozco-López Mariana, Orozco-Barocio Gerardo, Vázquez-Del Mercado Mónica, Muñoz-Valle José Francisco
Abstract excerpt
Systemic lupus erythematosus (SLE) is the prototype autoimmune rheumatic disease. The etiology of this disease is incompletely understood; however, environmental factors and genetic predisposition are involved. Cytokine-mediated immunity plays a crucial role in the pathogenesis of SLE. We investigate the association of interleukin-10 (IL-10) promoter polymorphisms and their haplotypes in SLE patients from the...
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