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Article

Genetic variation in C-reactive protein (CRP) gene may be associated with risk of systemic lupus erythematosus and CRP concentrations.

The Journal of rheumatology - 1 Nov 2008

Shih P Betty, Manzi Susan, Shaw Penny, Kenney Margaret, Kao Amy H, Bontempo Franklin, Barmada M Michael, Kammerer Candace, Kamboh M Ilyas

Abstract excerpt

OBJECTIVE: The gene coding for C-reactive protein (CRP) is located on chromosome 1q23.2, which falls within a linkage region thought to harbor a systemic lupus erythematosus (SLE) susceptibility gene. Recently, 2 single-nucleotide polymorphisms (SNP) in the CRP gene (+838, +2043) have been shown to be associated with CRP concentrations and/or SLE risk in a British family-based cohort. Our study was done to...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Lupus Erythematosus, Systemic

Share to Polymorphism, Single Nucleotide

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Source

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Identifiers

PMID: 18793001
DOI: 10.3899/jrheum.080262
PMCID: PMC2582591

Genes

CRP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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