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Association of - 717 A > G (rs2794521) CRP polymorphism with high cardiovascular risk by C-reactive protein in systemic lupus erythematosus patients.

Clinical rheumatology - 1 Mar 2023

Pesqueda-Cendejas Karen, Parra-Rojas Isela, Meza-Meza Mónica R, Mora-García Paulina E, Campos-López Bertha, Ruiz-Ballesteros Adolfo I, Montoya-Buelna Margarita, Rivera-Escoto Melissa, Moreno-Ortiz José M, Bautista-Herrera Luis A, Cerpa-Cruz Sergio, De la Cruz-Mosso Ulises

Abstract excerpt

INTRODUCTION: Systemic lupus erythematosus (SLE) is an autoimmune disease where genetic factors have been related to SLE susceptibility and disease severity. CRP polymorphisms have been associated with high C-reactive protein (CRP) serum levels, cardiovascular disease (CVD), and high clinical disease activity in SLE patients; however, the evidence is still inconclusive. OBJECTIVE: This study was aimed to assess...

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PMID: 36355253
DOI: 10.1007/s10067-022-06430-6

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