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Article

The aldehyde dehydrogenase 2 gene is associated with heroin dependence.

Drug and alcohol dependence - 1 Jan 2012

Wang Tzu-Yun, Lee Sheng-Yu, Chen Shiou-Lan, Chen Shih-Heng, Chu Chun-Hsien, Huang San-Yuan, Tzeng Nian-Sheng, Chang Yun-Hsuan, Wang Chen-Lin, Lee I Hui, Yeh Tzung Lieh, Yang Yen Kuang, Lu Ru-Band

Abstract excerpt

BACKGROUND: Determining the influences of genes involved in metabolizing dopamine and encoding dopamine receptors, such as the aldehyde dehydrogenase 2 (ALDH2) and dopamine D2 receptor/ankyrin repeat and kinase domain containing 1 (DRD2/ANKK1) genes, is critical for understanding addictive behavior. Therefore, we investigated the association between the ALDH2 and DRD2/ANKK1 Taq IA polymorphisms and heroin...

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Source

Identifiers

PMID: 21723677
DOI: 10.1016/j.drugalcdep.2011.06.008

Genes

ALDH2
DRD2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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