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Article

DRD2 and ANKK1 genes associate with late-onset heroin dependence in men.

The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry - 1 Oct 2019

Tsou Chang-Chih, Chou Han-Wei, Ho Pei-Shen, Kuo Shin-Chang, Chen Chun-Yen, Huang Chang-Chih, Liang Chih-Sung, Lu Ru-Band, Huang San-Yuan

Abstract excerpt

Objectives: Dopamine plays an important role in reward system of heroin dependence (HD), and dopaminergic D2 receptor (DRD2) gene is a candidate for the aetiology of HD. Ankyrin repeat and kinase domain containing 1 (ANKK1) gene is proximal to DRD2 and may influence its expression. We explored whether DRD2 and ANKK1 associate with occurrence of HD, and whether the genetic variants influence personality traits in...

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Identifiers

PMID: 28854834
DOI: 10.1080/15622975.2017.1372630

Genes

DRD2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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DRD2 and ANKK1 genes associate with late-onset heroin dependence in men.PMID 28854834Read ↗

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