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Article

The Role of Caspase Genes Polymorphisms in Genetic Susceptibility to Philadelphia-Negative Myeloproliferative Neoplasms in a Portuguese Population.

Pathology oncology research : POR - 1 Jul 2019

Azevedo Ana P, Silva Susana N, Reichert Alice, Lima Fernando, Júnior Esmeraldina, Rueff José

Abstract excerpt

Our main aim was to evaluate the role of caspases' genes SNPs in Philadelphia-chromosome negative chronic myeloproliferative neoplasms (PN-MPNs) susceptibility. A case-control study in 133 Caucasian Portuguese PN-MPNs patients and 281 matched controls was carried out, studying SNPs in apoptosis related caspases: rs1045485 and rs1035142 (CASP8), rs1052576, rs2308950, rs1132312 and (CASP9), and...

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Source

Identifiers

PMID: 29542026
DOI: 10.1007/s12253-018-0411-y

Genes

CASP9
JAK2
CASP10
CASP7
CASP8

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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