Article
Differential expression of apoptosis-related genes from death receptor pathway in chronic myeloproliferative diseases.
Journal of clinical pathology - 1 Jan 2011
Tognon Raquel, Gasparotto Elainy Patrícia Lino, Leroy Janine Marie Gisele, Oliveira Gislane Lelis Vilela, Neves Renata Peres, Carrara Rita de Cássia Viu, Kashima Simone, Covas Dimas Tadeu, Santana Mary, Souto Elizabeth Xisto, Zanichelli Maria Aparecida, Velano Carlos Eduardo Engel, Simões Belinda Pinto, Alberto Fernando Lopes, Miyashiro Kozue, de Souza Ana Maria, Amarante-Mendes Gustavo Pessini, de Castro Fabíola Attié
Abstract excerpt
BACKGROUND: Chronic myeloproliferative disorders (MPDs) are clonal haematopoietic stem cell malignancies characterised by an accumulation of mature myeloid cells in bone marrow and peripheral blood. Deregulation of the apoptotic machinery may be associated with MPD physiopathology. AIMS: To evalu...
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