Article
Detection of damaging nsSNPs on human caspase-cascades related to apoptotic signalling pathway.
Protein and peptide letters - 1 Sept 2013
Tomar Jinny, Gera V K, Chakraborty Chiranjib
Abstract excerpt
In tumorigenesis, cancer genetics and the related mutations have been the main topic of study these days. Caspases have been found to be actively involved in the process of apoptosis. Malfunction of apoptosis is one of the causes for cancerous tumors and different caspase mutations are related to that process. It has been found that two groups of caspases involved in this process apoptosis which are initiator...
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