Article
Association of caspase9 promoter polymorphisms with the susceptibility of AML in south Indian subjects.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Sept 2014
Cingeetham Anuradha, Vuree Sugunakar, Dunna Nageswara Rao, Gorre Manjula, Nanchari Santhoshi Rani, Edathara Prajitha Mohandas, Mekkaw Phannibhusan, Annamaneni Sandhya, Digumarthi Raghunadha Rao, Sinha Sudha, Satti Vishnupriya
Abstract excerpt
Abnormal apoptosis is one of the hallmarks of cancers including acute myeloid leukemia (AML), as it plays a pivotal role in precisely maintaining self-renewal, proliferation, and differentiation properties of hematopoietic stem cells (HSCs). Caspase9 (CASP9), an initiator caspase activated by mit...
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