Article
Association of TNF polymorphisms with JAK2 (V617F) myeloproliferative neoplasms in Brazilian patients.
Blood cells, molecules & diseases - 1 Mar 2016
Macedo Luciana Conci, de Cesare Quintero Fernanda, Pagliari-E-Silva Sara, Pagnano Katia Borgia Barbosa, Rodrigues Camila, de Alencar Josiane Bazzo, Sell Ana Maria, Visentainer Jeane Eliete Laguila
Abstract excerpt
The classical chromosome Philadelphia-negative myeloproliferative neoplasms (MPNs) are a group of disorders that share clinical, hematological, and histological features. Proinflammatory cytokines such as tumor necrosis factor-α (TNF-α) are elevated in patients with MPN. The aim of this study was to verify the association between the polymorphisms of TNF gene (-308G/A and -238 G/A) in BCR-ABL-negative MPN in our...
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