Article
Exome sequencing reveals the genetic landscape and frequent inactivation of PCDHB3 in Chinese rectal cancers.
The Journal of pathology - 1 Jun 2018
Ye Wen, Ling Shaoping, Liu Ran-Yi, Pan Zhi-Zhong, Wang Gaoyuan, Gao Shijuan, Wu Jiangxue, Cao Lihua, Dong Lili, Li Yingchang, Zhou Yi, Du Wuying, Meng Xiangqi, Chen Jinna, Guan Xinyuan, He Yulong, Pan Changchuan, Zheng Xf Steven, Lu Xuemei, Chen Shuai, Huang Wenlin
Abstract excerpt
Colorectal cancer (CRC) is the third most common cancer worldwide, with more than 1.3 million new cases and 690 000 deaths each year. In China, the incidence of CRC has increased dramatically due to dietary and lifestyle changes, to become the fifth leading cause of cancer-related death. Here, we performed whole-exome sequencing in 50 rectal cancer cases among the Chinese population as part of the International...
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