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Article

Integrated Profiling Identifies PLOD3 as a Potential Prognostic and Immunotherapy Relevant Biomarker in Colorectal Cancer.

Frontiers in immunology - 1 Jan 2021

Shi Junhong, Bao Meiyu, Wang Weifeng, Wu Xuan, Li Yueying, Zhao Changdong, Liu Weiwei

Abstract excerpt

Procollagen-Lysine,2-Oxoglutarate 5-Dioxygenase 3 (PLOD3) is related to a variety of human diseases. However, its function in Colorectal cancer (CRC) remains uncertain. PLOD3 expression was analyzed using The Cancer Genome Atlas (TCGA) pan-cancer data. DAVID was used for enrichment analysis of PLOD3-related genes. The correlation between PLOD3 expression and immune cell infiltration was evaluated. Four expression...

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CD8-Positive T-Lymphocytes
Databases, Factual
Immunotherapy
Microsatellite Instability
Procollagen-Lysine, 2-Oxoglutarate 5-Dioxygenase

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Tumor Microenvironment

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Identifiers

PMID: 34646265
DOI: 10.3389/fimmu.2021.722807
PMCID: PMC8503557

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