Article

Low BIN3 Expression is an Independent Predictor of Unfavorable Survival in Patients With Primary Colorectal Cancer

2017-12-01

Abstract excerpt

This study aimed to explore the mechanisms of bridging integrator-3 dysregulation, its prognostic value, and related signaling pathways in colorectal cancer . Bioinformatic analysis was performed based on the data from The Cancer Genome Atlas–colorectal cancer and Human Protein Atlas. Colorectal cancer cell lines, LoVo and HT29 cells, were used as in vitro cell model to assess the effect of demethylation on bridgi...

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Identifiers and source

Literature Corpus work: 1df4f725-e75f-5854-a97b-6d38b5d85482
DOI: 10.1177/1533034617747774
PMCID: PMC5762098

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