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Article

Genome-wide association study in Finnish twins highlights the connection between nicotine addiction and neurotrophin signaling pathway.

Addiction biology - 1 May 2019

Hällfors Jenni, Palviainen Teemu, Surakka Ida, Gupta Richa, Buchwald Jadwiga, Raevuori Anu, Ripatti Samuli, Korhonen Tellervo, Jousilahti Pekka, Madden Pamela A F, Kaprio Jaakko, Loukola Anu

Abstract excerpt

The heritability of nicotine dependence based on family studies is substantial. Nevertheless, knowledge of the underlying genetic architecture remains meager. Our aim was to identify novel genetic variants responsible for interindividual differences in smoking behavior. We performed a genome-wide association study on 1715 ever smokers ascertained from the population-based Finnish Twin Cohort enriched for heavy...

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PMID: 29532581
DOI: 10.1111/adb.12618
PMCID: PMC6519128

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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