Article
Genome-wide association study on detailed profiles of smoking behavior and nicotine dependence in a twin sample.
Molecular psychiatry - 1 May 2014
Loukola A, Wedenoja J, Keskitalo-Vuokko K, Broms U, Korhonen T, Ripatti S, Sarin A-P, Pitkäniemi J, He L, Häppölä A, Heikkilä K, Chou Y-L, Pergadia M L, Heath A C, Montgomery G W, Martin N G, Madden P A F, Kaprio J
Abstract excerpt
Smoking is a major risk factor for several somatic diseases and is also emerging as a causal factor for neuropsychiatric disorders. Genome-wide association (GWA) and candidate gene studies for smoking behavior and nicotine dependence (ND) have disclosed too few predisposing variants to account for the high estimated heritability. Previous large-scale GWA studies have had very limited phenotypic definitions of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.