Article
Large-scale profiling of noncoding RNA function in yeast.
PLoS genetics - 1 Mar 2018
Parker Steven, Fraczek Marcin G, Wu Jian, Shamsah Sara, Manousaki Alkisti, Dungrattanalert Kobchai, de Almeida Rogerio Alves, Invernizzi Edith, Burgis Tim, Omara Walid, Griffiths-Jones Sam, Delneri Daniela, O'Keefe Raymond T
Abstract excerpt
Noncoding RNAs (ncRNAs) are emerging as key regulators of cellular function. We have exploited the recently developed barcoded ncRNA gene deletion strain collections in the yeast Saccharomyces cerevisiae to investigate the numerous ncRNAs in yeast with no known function. The ncRNA deletion collection contains deletions of tRNAs, snoRNAs, snRNAs, stable unannotated transcripts (SUTs), cryptic unstable transcripts...
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