Article
Functional genomics of genes with small open reading frames (sORFs) in S. cerevisiae.
Genome research - 1 Mar 2006
Kastenmayer James P, Ni Li, Chu Angela, Kitchen Lauren E, Au Wei-Chun, Yang Hui, Carter Carole D, Wheeler David, Davis Ronald W, Boeke Jef D, Snyder Michael A, Basrai Munira A
Abstract excerpt
Genes with small open reading frames (sORFs; <100 amino acids) represent an untapped source of important biology. sORFs largely escaped analysis because they were difficult to predict computationally and less likely to be targeted by genetic screens. Thus, the substantial number of sORFs and their potential importance have only recently become clear. To investigate sORF function, we undertook the first functional...
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