Article
Associations between TOMM40 Poly-T Repeat Variants and Dementia in Cases with Parkinsonism.
Journal of Parkinson's disease - 1 Jan 2016
Lindqvist Daniel, Prokopenko Inga, Londos Elisabet, Middleton Lefkos, Hansson Oskar
Abstract excerpt
BACKGROUND: Mitochondrial dysfunction has been implicated in the pathophysiology of Parkinson's disease (PD)-related pathologies. OBJECTIVE: To investigate the role of the Translocase of the Outer Mitochondrial Membrane 40 homolog (TOMM40) variants in PD without dementia (PDND), PD with dementia (PDD) and in Dementia with Lewy bodies (DLB). METHODS: 248 individuals, including 92 PDND, 55 PDD, and 101 DLB, were...
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