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Article

LPA kringle IV type 2 is associated with type 2 diabetes in a Chinese population with very high cardiovascular risk.

Journal of lipid research - 1 May 2018

Mu-Han-Ha-Li 迪丽达尔木汗哈力 Di-Li-Da-Er, Zhai 翟天羽 Tian-Yu, Ling 凌雁 Yan, Gao 高鑫 Xin

Abstract excerpt

The connection between lipoprotein (a) [Lp(a)] levels and the risks of cardiovascular disease and diabetes remains poorly understood. Lp(a) is encoded by the LPA gene, and evidence suggests that the kringle IV type 2 (KIV-2) variant is particularly important to Lp(a) isoform size. A large isoform size, represented as a high number of KIV-2 repeats in LPA, is associated with low serum Lp(a) concentrations and an...

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Identifiers

PMID: 29511049
DOI: 10.1194/jlr.P082792
PMCID: PMC5928429

Genes

LPA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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LPA kringle IV type 2 is associated with type 2 diabetes in a Chinese population with very high cardiovascular risk.PMID 29511049Read ↗

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