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Article

17-β estradiol increases parvalbumin levels in Pvalb heterozygous mice and attenuates behavioral phenotypes with relevance to autism core symptoms.

Molecular autism - 1 Jan 2018

Filice Federica, Lauber Emanuel, Vörckel Karl Jakob, Wöhr Markus, Schwaller Beat

Abstract excerpt

Background: Autism spectrum disorder (ASD) is a group of neurodevelopmental disorders characterized by two core symptoms: impaired social interaction and communication, and restricted, repetitive behaviors and interests. The pathophysiology of ASD is not yet fully understood, due to a plethora of genetic and environmental risk factors that might be associated with or causal for ASD. Recent findings suggest that...

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Identifiers

PMID: 29507711
DOI: 10.1186/s13229-018-0199-3
PMCID: PMC5833085

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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