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Article

A homeostatic clock sets daughter centriole size in flies.

The Journal of cell biology - 2 Apr 2018

Aydogan Mustafa G, Wainman Alan, Saurya Saroj, Steinacker Thomas L, Caballe Anna, Novak Zsofia A, Baumbach Janina, Muschalik Nadine, Raff Jordan W

Abstract excerpt

Centrioles are highly structured organelles whose size is remarkably consistent within any given cell type. New centrioles are born when Polo-like kinase 4 (Plk4) recruits Ana2/STIL and Sas-6 to the side of an existing "mother" centriole. These two proteins then assemble into a cartwheel, which grows outwards to form the structural core of a new daughter. Here, we show that in early Drosophila melanogaster...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 29500190
DOI: 10.1083/jcb.201801014
PMCID: PMC5881511

Genes

STIL

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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