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Ana1/CEP295 is an essential player in the centrosome maintenance program regulated by Polo kinase and the PCM

10 Jan 2024

Abstract excerpt

Centrioles are part of centrosomes and cilia, which are microtubule organising centres (MTOC) with diverse functions. Despite their stability, centrioles can disappear during differentiation, such as in oocytes, but little is known about the regulation of their structural integrity. Our previous research revealed that the pericentriolar material (PCM) that surrounds centrioles and its recruiter, Polo kinase, are...

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PMID: 38200359
DOI: 10.1038/s44319-023-00020-6

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