Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The E2F-DP1 Transcription Factor Complex Regulates Centriole Duplication in Caenorhabditis elegans.

G3 (Bethesda, Md.) - 15 Jan 2016

Miller Jacqueline G, Liu Yan, Williams Christopher W, Smith Harold E, O'Connell Kevin F

Abstract excerpt

Centrioles play critical roles in the organization of microtubule-based structures, from the mitotic spindle to cilia and flagella. In order to properly execute their various functions, centrioles are subjected to stringent copy number control. Central to this control mechanism is a precise duplication event that takes place during S phase of the cell cycle and involves the assembly of a single daughter centriole...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Animals, Genetically Modified
Share to Caenorhabditis elegans Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Centrioles

Share to E2F Transcription Factors

Share to Genes, Lethal

Share to Genome, Helminth

Share to Multiprotein Complexes

Share to Transcription Factor DP1

Source

Open in PubMed Open full text

Identifiers

PMID: 26772748
DOI: 10.1534/g3.115.025577
PMCID: PMC4777132

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The E2F-DP1 Transcription Factor Complex Regulates Centriole Duplication in Caenorhabditis elegans.PMID 26772748Read ↗

The Chromatin Remodeling Protein CHD-1 and the EFL-1/DPL-1 Transcription Factor Cooperatively Down Regulate CDK-2 to Control SAS-6 Levels and Centriole NumberSemantic proximity Read ↗

Protein Phosphatase 1 Down Regulates ZYG-1 Levels to Limit Centriole Duplication.Semantic proximity Read ↗

Protein phosphatase 1 down regulates ZYG-1 levels to limit centriole duplicationSemantic proximity Read ↗

The C. elegans zyg-1 gene encodes a regulator of centrosome duplication with distinct maternal and paternal roles in the embryo.Semantic proximity Read ↗

The conserved protein SZY-20 opposes the Plk4-related kinase ZYG-1 to limit centrosome size.Semantic proximity Read ↗

DSAS-6 organizes a tube-like centriole precursor, and its absence suggests modularity in centriole assembly.Semantic proximity Read ↗

Suppressors of zyg-1 define regulators of centrosome duplication and nuclear association in Caenorhabditis elegans.Semantic proximity Read ↗

<i>Spd-2</i> Gene Duplication Suggests Cell-Type Specific Assembly Mechanisms of Pericentriolar MaterialSemantic proximity Read ↗

The candidate MAP kinase phosphorylation substrate DPL-1 (DP) promotes expression of the MAP kinase phosphatase LIP-1 in C. elegans germ cells.Semantic proximity Read ↗

Flies without centrioles.Semantic proximity Read ↗

SAS-4 is a C. elegans centriolar protein that controls centrosome size.Semantic proximity Read ↗

Distinct D-box Motifs in SPD-2 Mediate APC/C <sup>FZR-1</sup> -Dependent Degradation and Centrosomal Localization in <i>Caenorhabditis elegans</i> EmbryosSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.