Article

Adaptable centriole biogenesis via the intrinsically disordered protein ALMS1

2025-06-27

Abstract excerpt

Biogenesis of subcellular structures like centrioles is viewed as a physical transformation wherein elementary constituents form order without preexisting templates. Centrioles grow with precision from a composite scaffold known as the cartwheel, which is thought to self-assemble without templates and disassemble following centriole growth; however, the mechanism governing cartwheel assembly-disassembly dynamics r...

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Literature Corpus work: 3d153c72-7321-52e8-8756-762f95a18fc2
DOI: 10.1101/2025.06.26.661604

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