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Outcomes and prognosis of haploidentical haematopoietic stem cell transplantation in children with FLT3-ITD mutated acute myeloid leukaemia.

Bone marrow transplantation - 1 Jun 2024

Shang Qianwen, Bai Lu, Cheng Yifei, Suo Pan, Hu Guanhua, Yan Chenhua, Wang Yu, Zhang Xiaohui, Xu Lanping, Liu Kaiyan, Huang Xiaojun

Abstract excerpt

The presence of internal tandem duplication mutations in the FMS-like tyrosine kinase 3 receptor (FLT3-ITD) is a poor prognostic predictor in paediatric patients with acute myeloid leukaemia (AML). We evaluated the treatment outcomes and prognostic factors of 45 paediatric patients with FLT3-ITD AML who achieved complete remission before haploidentical haematopoietic stem cell transplantation (haplo-HSCT) at our...

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Identifiers

PMID: 38443705
DOI: 10.1038/s41409-024-02214-5

Genes

FLT3
EFS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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