Article
Prognostic implications of miR-146b expression and its functional role in papillary thyroid carcinoma.
The Journal of clinical endocrinology and metabolism - 1 Feb 2013
Chou Chen-Kai, Yang Kuender D, Chou Fong-Fu, Huang Chao-Cheng, Lan Yueh-Wen, Lee Ya-Fang, Kang Hong-Yo, Liu Rue-Tsuan
Abstract excerpt
CONTEXT: Recent studies suggest that miR-146b deregulation in papillary thyroid carcinoma (PTC) was associated with advanced tumor characteristics. However, the influence of miR-146b expression on the prognosis of PTC remains unknown. We sought to correlate tumor expression levels of miR-146b with the prognosis of a previously reported PTC cohort and reveal the underlying mechanisms via a PTC cell line model....
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