Article
MicroRNAs miR-146-5p and let-7f as prognostic tools for aggressive papillary thyroid carcinoma: a case report.
Arquivos brasileiros de endocrinologia e metabologia - 1 Nov 2012
Geraldo Murilo Vieira, Fuziwara Cesar Seigi, Friguglieti Celso Ubirajara Moretto, Costa Ricardo Borges, Kulcsar Marco Aurélio Vamondes, Yamashita Alex Shimura, Kimura Edna Teruko
Abstract excerpt
Papillary thyroid cancer (PTC) is the most incident histotype of thyroid cancer. A certain fraction of PTC cases (5%) are irresponsive to conventional treatment, and refractory to radioiodine therapy. The current prognostic factors for aggressiveness are mainly based on tumor size, the presence of lymph node metastasis, extrathyroidal invasion and, more recently, the presence of the BRAFT1799A mutation. MicroRNAs...
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