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Article

MicroRNA-146b: A Novel Biomarker and Therapeutic Target for Human Papillary Thyroid Cancer.

International journal of molecular sciences - 15 Mar 2017

Chou Chen-Kai, Liu Rue-Tusan, Kang Hong-Yo

Abstract excerpt

Papillary thyroid cancer (PTC) is the most common tumor subtype of thyroid cancer. However, not all PTCs are responsive to current surgical and radioiodine treatment. The well-established clinical prognostic factors include tumor size, lymph node/distal metastasis, and extrathyroidal invasion. The RET/PTC-RAS-BRAF linear molecular signaling cascade is known to mediate PTC pathogenesis. However, whether presence...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 28294980
DOI: 10.3390/ijms18030636
PMCID: PMC5372649

Genes

BRAF
RET

Provenance

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