Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

FAM13A and POM121C are candidate genes for fasting insulin: functional follow-up analysis of a genome-wide association study.

Diabetologia - 1 May 2018

Lundbäck Veroniqa, Kulyte Agne, Strawbridge Rona J, Ryden Mikael, Arner Peter, Marcus Claude, Dahlman Ingrid

Abstract excerpt

AIMS/HYPOTHESIS: By genome-wide association meta-analysis, 17 genetic loci associated with fasting serum insulin (FSI), a marker of systemic insulin resistance, have been identified. To define potential culprit genes in these loci, in a cross-sectional study we analysed white adipose tissue (WAT) expression of 120 genes in these loci in relation to systemic and adipose tissue variables, and functionally evaluated...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adipocytes
Share to Adipogenesis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Adipose Tissue

Share to Adiposity

Share to Fasting

Share to GTPase-Activating Proteins

Share to Lipolysis

Share to Sweden

Source

Open in PubMed Open full text

Identifiers

PMID: 29487953
DOI: 10.1007/s00125-018-4572-8
PMCID: PMC6448992

Genes

LIPE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

FAM13A and POM121C are candidate genes for fasting insulin: functional follow-up analysis of a genome-wide association study.PMID 29487953Read ↗

Global Gene Expression Profiles of Subcutaneous Adipose and Muscle From Glucose-Tolerant, Insulin-Sensitive, and Insulin-Resistant Individuals Matched for BMISemantic proximity Read ↗

Genome-Wide Discovery Reveals Adipose-Specific and Systemic Regulators of Insulin ResistanceSemantic proximity Read ↗

Genome-wide association study identifies novel loci association with fasting insulin and insulin resistance in African Americans.Semantic proximity Read ↗

FAM13A affects body fat distribution and adipocyte function.Semantic proximity Read ↗

Characterisation of non-obese diabetic patients with marked insulin resistance identifies a novel familial partial lipodystrophy-associated PPARγ mutation (Y151C).Semantic proximity Read ↗

Common genetic variation in the SERPINF1 locus determines overall adiposity, obesity-related insulin resistance, and circulating leptin levels.Semantic proximity Read ↗

Predictive network modeling in human induced pluripotent stem cells identifies key driver genes for insulin responsivenessSemantic proximity Read ↗

Association of the IGF1 gene with fasting insulin levels.Semantic proximity Read ↗

Folliculin-interacting protein FNIP2 impacts on overweight and obesity through a polymorphism in a conserved 3' untranslated region.Semantic proximity Read ↗

Effects of Genetic Loci Associated with Central Obesity on Adipocyte Lipolysis.Semantic proximity Read ↗

Relationship of Fat Mass Ratio, a Biomarker for Lipodystrophy, With Cardiometabolic TraitsSemantic proximity Read ↗

Integrative genomic analysis implicates limited peripheral adipose storage capacity in the pathogenesis of human insulin resistance.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.