Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Effects of Genetic Loci Associated with Central Obesity on Adipocyte Lipolysis.

PloS one - 1 Jan 2016

Strawbridge Rona J, Laumen Helmut, Hamsten Anders, Breier Michaela, Grallert Harald, Hauner Hans, Arner Peter, Dahlman Ingrid

Abstract excerpt

OBJECTIVES: Numerous genetic loci have been associated with measures of central fat accumulation, such as waist-to-hip ratio adjusted for body mass index (WHRadjBMI). However the mechanisms by which genetic variations influence obesity remain largely elusive. Lipolysis is a key process for regulation of lipid storage in adipocytes, thus is implicated in obesity and its metabolic complications. Here, genetic...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adipocytes
Share to Adolescent
Share to Body Mass Index

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to VEGFA gene

Share to Lipolysis

Share to Obesity, Abdominal

Share to Polymorphism, Single Nucleotide

Source

Open in PubMed Open full text

Identifiers

PMID: 27104953
DOI: 10.1371/journal.pone.0153990
PMCID: PMC4841524

Genes

CMIP
KREMEN1
PLXND1
VEGFA
ZNRF3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Effects of Genetic Loci Associated with Central Obesity on Adipocyte Lipolysis.PMID 27104953Read ↗

Shared Genetic Loci For Body Fat Storage And Adipocyte Lipolysis In HumansSemantic proximity Read ↗

Genome-wide association study of adipocyte lipolysis in the GENetics of adipocyte lipolysis (GENiAL) cohort.Semantic proximity Read ↗

Genome-wide scan and fine-mapping of rare nonsynonymous associations implicates intracellular lipolysis genes in fat distribution and cardio-metabolic riskSemantic proximity Read ↗

New genetic loci link adipose and insulin biology to body fat distribution.Semantic proximity Read ↗

Population sequencing of two endocannabinoid metabolic genes identifies rare and common regulatory variants associated with extreme obesity and metabolite level.Semantic proximity Read ↗

Sex Differences in Genomic Drivers of Adipose Distribution and Related Cardiometabolic DisordersSemantic proximity Read ↗

Epigenome-wide association in adipose tissue from the METSIM cohortSemantic proximity Read ↗

Prostaglandin E2-EP4 Axis Promotes Lipolysis and Fibrosis in Adipose Tissue Leading to Ectopic Fat Deposition and Insulin Resistance.Semantic proximity Read ↗

Integration of human adipocyte chromosomal interactions with adipose gene expression prioritizes obesity-related genes from GWAS.Semantic proximity Read ↗

Meta-analysis of genome-wide association studies for body fat distribution in 694,649 individuals of European ancestrySemantic proximity Read ↗

Relationship of Fat Mass Ratio, a Biomarker for Lipodystrophy, With Cardiometabolic TraitsSemantic proximity Read ↗

Systems genetics analysis of human body fat distribution genes identifies Wnt signaling and mitochondrial activity in adipocytesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.