Article
Tumor Protein p53 (TP53) Gene and Left Main Coronary Artery Disease.
Angiology - 1 Sept 2018
Kolovou Vana, Tsipis Angelos, Mihas Constantinos, Katsiki Niki, Vartela Vasiliki, Koutelou Maria, Manolopoulou Dionisia, Leondiadis Evaggelos, Iakovou Ioannis, Mavrogieni Sophie, Kolovou Genovefa
Abstract excerpt
Patients with left main (LM) coronary artery disease (CAD) are at the highest risk of cardiovascular events. We evaluated possible gene polymorphisms of tumor protein 53 ( TP53, rs1042522, p.Arg72Pro) that can differentiate LM-CAD from patients with more peripheral CAD (MP-CAD) and healthy participants (control group) in 520 individuals (LM-CAD, n = 175; MP-CAD, n = 185; and control group, n = 160). Patients with...
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