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Article

Altered p53 Gene Expression in Coronary Artery Disease Patients with Dyslipidemia: Implications for Atherogenesis.

High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension - 1 May 2026

Gopan M Reshma, Chandrasekaran Deepika, Roy D Dinesh, Muninathan Natarajan, Mahila S, Pr Radhika

Abstract excerpt

INTRODUCTION: A concerning increase in coronary artery disease (CAD) among younger Indians calls attention to genetic biomarkers that indicate early vascular stress. The tumor suppressor gene p53, known primarily for its oncogenic role, also modulates vascular apoptosis and inflammation. However, its link with metabolic and nitrosative stress in CAD remains underexplored. AIM: To determine the potential of p53 as...

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Identifiers

PMID: 41533273
DOI: 10.1007/s40292-025-00776-z

Genes

CAD

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 17 Oct 2026.

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