TP53 codon 72 polymorphism is associated with coronary artery disease in Chilean subjects.

doi:10.1159/000321206

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TP53 codon 72 polymorphism is associated with coronary artery disease in Chilean subjects.

Medical principles and practice : international journal of the Kuwait University, Health Science Centre - 1 Jan 2011

Caamaño José, Saavedra Nicolás, Jaramillo Priscilla C, Lanas Cecilia, Lanas Fernando, Salazar Luis A

Abstract excerpt

OBJECTIVE: To investigate the possible association between the codon 72 polymorphism (Pro72Arg, rs1042522) of the tumor suppressor gene (TP53) and the presence of coronary artery disease (CAD) in Chilean subjects. SUBJECTS AND METHODS: A total of 209 unrelated patients with a diagnosis of CAD confirmed by angiography (33-74 years old) and 216 healthy controls (30-68 years old) were included in this study. The...

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PMID: 21252575
DOI: 10.1159/000321206

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