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Article

CD18-mediated adhesion is required for the induction of a proinflammatory phenotype in lung epithelial cells by mononuclear cell-derived extracellular vesicles.

Experimental cell research - 1 Apr 2018

Neri Tommaso, Scalise Valentina, Passalacqua Ilaria, Giusti Ilaria, Lombardi Stefania, Balia Cristina, D'Alessandro Delfo, Berrettini Stefano, Pedrinelli Roberto, Paggiaro Pierluigi, Dolo Vincenza, Celi Alessandro

Abstract excerpt

Extracellular vesicles are submicron vesicles that upregulate the synthesis of proinflammatory mediators by lung epithelial cells. We investigated whether these structures adhere to lung epithelial cells, and whether adhesion is a prerequisite for their proinflammatory activity. Extracellular vesicles were generated by stimulation of normal human mononuclear cells with the calcium ionophore A23187, and labelled...

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Identifiers

PMID: 29476835
DOI: 10.1016/j.yexcr.2018.02.023

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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