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Article

Extracellular Vesicles as Central Mediators of COPD Pathophysiology

1 Nov 2021

Abstract excerpt

Chronic obstructive pulmonary disease (COPD) is a complex, heterogeneous, smoking-related disease of significant global impact. The complex biology of COPD is ultimately driven by a few interrelated processes, including proteolytic tissue remodeling, innate immune inflammation, derangements of the host-pathogen response, aberrant cellular phenotype switching, and cellular senescence, among others. Each of these...

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PMID: 34724435
DOI: 10.1146/annurev-physiol-061121-035838

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