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Article

Extracellular vesicles derived from Gram-negative bacteria, such as Escherichia coli, induce emphysema mainly via IL-17A-mediated neutrophilic inflammation.

Journal of immunology (Baltimore, Md. : 1950) - 1 Apr 2015

Kim You-Sun, Lee Won-Hee, Choi Eun-Jeong, Choi Jun-Pyo, Heo Young Joo, Gho Yong Song, Jee Young-Koo, Oh Yeon-Mok, Kim Yoon-Keun

Abstract excerpt

Recent evidence indicates that Gram-negative bacteria-derived extracellular vesicles (EVs) in indoor dust can evoke neutrophilic pulmonary inflammation, which is a key pathology of chronic obstructive pulmonary disease (COPD). Escherichia coli is a ubiquitous bacterium present in indoor dust and secretes nanometer-sized vesicles into the extracellular milieu. In the current study, we evaluated the role of E....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 25716999
DOI: 10.4049/jimmunol.1402268

Genes

TNF
TLR4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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