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Article

Identification of Known and Novel Long Noncoding RNAs Potentially Responsible for the Effects of Bone Mineral Density (BMD) Genomewide Association Study (GWAS) Loci.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research - 1 Aug 2022

Abood Abdullah, Mesner Larry, Rosenow Will, Al-Barghouthi Basel M, Horowitz Nina, Morgan Elise F, Gerstenfeld Louis C, Farber Charles R

Abstract excerpt

Osteoporosis, characterized by low bone mineral density (BMD), is the most common complex disease affecting bone and constitutes a major societal health problem. Genome-wide association studies (GWASs) have identified over 1100 associations influencing BMD. It has been shown that perturbations to long noncoding RNAs (lncRNAs) influence BMD and the activities of bone cells; however, the extent to which lncRNAs are...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 35695880
DOI: 10.1002/jbmr.4622
PMCID: PMC9545622

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