Article
Effective polyploidy causes phenotypic delay and influences bacterial evolvability.
PLoS biology - 1 Feb 2018
Sun Lei, Alexander Helen K, Bogos Balazs, Kiviet Daniel J, Ackermann Martin, Bonhoeffer Sebastian
Abstract excerpt
Whether mutations in bacteria exhibit a noticeable delay before expressing their corresponding mutant phenotype was discussed intensively in the 1940s to 1950s, but the discussion eventually waned for lack of supportive evidence and perceived incompatibility with observed mutant distributions in fluctuation tests. Phenotypic delay in bacteria is widely assumed to be negligible, despite the lack of direct...
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