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Article

Unpredictable repeatability in molecular evolution.

Proceedings of the National Academy of Sciences of the United States of America - 27 Sept 2022

Das Suman G, Krug Joachim

Abstract excerpt

The extent of parallel evolution at the genotypic level is quantitatively linked to the distribution of beneficial fitness effects (DBFE) of mutations. The standard view, based on light-tailed distributions (i.e., distributions with finite moments), is that the probability of parallel evolution in duplicate populations is inversely proportional to the number of available mutations and, moreover, that the DBFE is...

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Identifiers

PMID: 36122210
DOI: 10.1073/pnas.2209373119
PMCID: PMC9522380

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