Article
Big things from a little RNA.
Trends in cell biology - 1 Sept 2003
Moberg Kenneth H, Hariharan Iswar K
Abstract excerpt
In a recent study, Brennecke and colleagues show that bantam, a previously elusive Drosophila gene that promotes tissue growth, encodes a microRNA. The bantam microRNA regulates cell number in vivo and inhibits cell death by binding to the mRNA of the pro-apoptotic gene hid. These findings demonstrate that a single, tiny Drosophila RNA can regulate organ and organism size and link the nascent field of microRNA...
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