Article
Maternal H3K27me3 controls DNA methylation-independent imprinting.
Nature - 27 Jul 2017
Inoue Azusa, Jiang Lan, Lu Falong, Suzuki Tsukasa, Zhang Yi
Abstract excerpt
Mammalian sperm and oocytes have different epigenetic landscapes and are organized in different fashions. After fertilization, the initially distinct parental epigenomes become largely equalized with the exception of certain loci, including imprinting control regions. How parental chromatin becomes equalized and how imprinting control regions escape from this reprogramming is largely unknown. Here we profile...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
