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Article

Life cycle synchronization is a viral drug resistance mechanism.

PLoS computational biology - 1 Feb 2018

Neagu Iulia A, Olejarz Jason, Freeman Mark, Rosenbloom Daniel I S, Nowak Martin A, Hill Alison L

Abstract excerpt

Viral infections are one of the major causes of death worldwide, with HIV infection alone resulting in over 1.2 million casualties per year. Antiviral drugs are now being administered for a variety of viral infections, including HIV, hepatitis B and C, and influenza. These therapies target a specific phase of the virus's life cycle, yet their ultimate success depends on a variety of factors, such as adherence to...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 29447150
DOI: 10.1371/journal.pcbi.1005947
PMCID: PMC5813899

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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