Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Clinico-pathological and molecular characterization of diffuse midline gliomas: is there a prognostic significance?

Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology - 1 Mar 2021

Manjunath Niveditha, Jha Prerana, Singh Jyotsna, Raheja Amol, Kaur Kavneet, Suri Ashish, Garg Ajay, Sharma Mehar Chand, Sarkar Chitra, Mohan Madan, Mani Kalaivani, Suri Vaishali

Abstract excerpt

PURPOSE: H3K27M mutant diffuse midline gliomas (DMGs) are considered grade IV irrespective of histological features and have dismal prognosis. We evaluated clinico-pathologic, radiological, and molecular characteristics of DMGs across all ages. METHODS: One twenty-six DMGs were identified over 10 years. Immunohistochemistry was done for H3K27M, ATRX, IDH1, and p53, and Sanger sequencing performed for IDH1 and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Brain Neoplasms
Share to Child

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Glioma

Share to Histones

Share to Isocitrate Dehydrogenase

Share to Mutation

Share to Prognosis

Source

Identifiers

PMID: 32666407
DOI: 10.1007/s10072-020-04489-0

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Clinico-pathological and molecular characterization of diffuse midline gliomas: is there a prognostic significance?PMID 32666407Read ↗

Clinical, radiologic, and genetic characteristics of histone H3 K27M-mutant diffuse midline gliomas in adultsSemantic proximity Read ↗

Survival analysis of adult midline-located gliomas and diffuse midline gliomas: beyond the H3K27 mutation paradigm.Semantic proximity Read ↗

H3K27M-Altered Diffuse Midline Gliomas Among Adult Patients: A Systematic Review of Clinical Features and Survival Analysis.Semantic proximity Read ↗

H3 K27M-mutant diffuse midline gliomas in different anatomical locations.Semantic proximity Read ↗

Characteristics of H3K27M-mutant diffuse gliomas with a non-midline location.Semantic proximity Read ↗

Characteristics of H3K27M-mutant diffuse gliomas with a non-midline locationSemantic proximity Read ↗

Adult diffuse midline gliomas H3 K27-altered: review of a redefined entity.Semantic proximity Read ↗

Adult diffuse midline gliomas: Clinical, radiological, and genetic characteristics.Semantic proximity Read ↗

Diffuse Midline Gliomas With Histone H3 K27M Mutation in Adults and Children: A Retrospective Series of 164 Cases.Semantic proximity Read ↗

Identification of prognostic markers in diffuse midline gliomas H3K27M-mutant.Semantic proximity Read ↗

H3K27-altered diffuse midline gliomas with MAPK pathway alterations: Prognostic and therapeutic implications.Semantic proximity Read ↗

The prognostic significance of HIST1H3B/C and H3F3A K27M mutations in diffuse midline gliomas is influenced by patient age.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.