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Article

Colorectal Cancer Risk by Genetic Variants in Populations With and Without Colonoscopy History.

JNCI cancer spectrum - 1 Feb 2021

Guo Feng, Chen Xuechen, Chang-Claude Jenny, Hoffmeister Michael, Brenner Hermann

Abstract excerpt

Background: Polygenic risk scores (PRS), which are derived from results of large genome-wide association studies, are increasingly propagated for colorectal cancer (CRC) risk stratification. The majority of studies included in the large genome-wide association studies consortia were conducted in the United States and Germany, where colonoscopy with detection and removal of polyps has been widely practiced over...

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Identifiers

PMID: 33644683
DOI: 10.1093/jncics/pkab008
PMCID: PMC7898082

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