Colonoscopy and Reduction of Colorectal Cancer Risk by Molecular Tumor Subtypes: A Population-Based Case-Control Study.

doi:10.14309/ajg.0000000000000819

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Article

Colonoscopy and Reduction of Colorectal Cancer Risk by Molecular Tumor Subtypes: A Population-Based Case-Control Study.

The American journal of gastroenterology - 1 Dec 2020

Hoffmeister Michael, Bläker Hendrik, Jansen Lina, Alwers Elizabeth, Amitay Efrat L, Carr Prudence R, Kloor Matthias, Herpel Esther, Roth Wilfried, Chang-Claude Jenny, Brenner Hermann

Abstract excerpt

INTRODUCTION: In previous studies, the protective effect of colonoscopy was generally stronger for distal colorectal cancer than for proximal colorectal cancer (CRC). This study aimed to investigate whether reduction of CRC risk through colonoscopy varies according to major tumor markers and pathways of CRC. METHODS: This is a population-based case-control study from Germany, including 2,132 patients with a first...

Topics

Adenoma
Aged
Aged, 80 and over
Biomarkers, Tumor
Case-Control Studies
Colonoscopy
Colorectal Neoplasms
CpG Islands
DNA Methylation
Female

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Germany

Humans

Male

Microsatellite Instability

Middle Aged

Mutation

Proto-Oncogene Proteins B-raf

Source

Open in PubMed

Identifiers

PMID: 32858564
DOI: 10.14309/ajg.0000000000000819

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-32858564-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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