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Article

PIK3CA and TP53 mutations predict overall survival of stage II/III colorectal cancer patients.

World journal of gastroenterology - 7 Feb 2018

Li A-Jian, Li Hua-Guang, Tang Er-Jiang, Wu Wei, Chen Ying, Jiang Hui-Hong, Lin Mou-Bin, Yin Lu

Abstract excerpt

AIM: To investigate the predictive value of PIK3CA and TP53 mutation status in colorectal cancer (CRC) patients treated with 5-fluorouracil-based chemotherapy. METHODS: In this study, a total of 315 patients with histologically proven CRC were enrolled from Yangpu Hospital affiliated to Shanghai Tongji University between 2007 and 2011. Of these patients, 241 with stage II/III CRC received 5-fluorouracil-based...

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Identifiers

PMID: 29434452
DOI: 10.3748/wjg.v24.i5.631
PMCID: PMC5799864

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